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Pharmacology

 

Meduri 1998: Meduri protocol for unresolving ARDS (JAMA) (1998)

 

SCCOPE: Steroids for COPD exacerbations (NEJM) (1999)

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MAPPET-3: Alteplase with or without heparin for sub massive PE (NEJM) (2002)

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LaSRS: Late rescue steroids for ARDS (NEJM) (2006)

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Meduri 2007: Meduri protocol for early ARDS (CHEST) (2007)

 

Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome (NEJM) (2010)

 

MOPETT: Alteplase for moderate PE (Am J Cardiol) (2013)

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AARC Clinical Practice Guideline: Effectiveness of Pharmacologic Airway Clearance Therapies in Hospitalized Patients (Respiratory Care) (2015)

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Sodium bicarbonate therapy for patients with severe metabolic acidemia in the intensive care unit (BICAR-ICU): a multicenter, open-label, randomized controlled, phase 3 trial (Lancet) (2018)

 

ROSE: Cisatracurium for early ARDS (NEJM) (2019)

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Inhaled Pulmonary Vasodilators and Thoracic Organ Transplantation: Does Evidence Support Its Use and Cost Benefit? (Semin Cardiothorac Vasc Anesth) (2019)

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DEXA-ARDS: Dexamethasone for early ARDS (Lancet) (2020)

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ACTT-1: Remdesivir for COVID-19 (NEJM) (2020)

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Editorial overview: Respiratory: Pulmonary pharmacology–The emergence of new treatments in pulmonary medicine is finally providing real therapeutic perspectives (Cur Opin Pharmacol) (2021)

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Inhaled pulmonary vasodilators: a narrative review (Ann Transl Med) (2021)

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Inhaled pulmonary vasodilators are not associated with improved gas exchange in mechanically ventilated patients with COVID-19: A retrospective cohort study (J Crit Care) (2022)

 

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomized, controlled, open-label, platform trial (Lancet) (2023) 

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Do We Need to Administer Fludrocortisone in Addition to Hydrocortisone in Adult Patients With Septic Shock? An Updated Systematic Review With Bayesian Network Meta-Analysis of Randomized Controlled Trials and an Observational Study With Target Trial Emulation (Critical Care Medicine) (2023)

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Hydrocortisone in Severe Community-Acquired Pneumonia (NEJM) (2023)

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Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia (NEJM) (2023)

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CAPE COD: Hydrocortisone for severe CAP (NEJM) (2023)

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Mucolytic Medications (StatPearls)

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Inhaled Pulmonary Vasodilators for the Treatment of Right Ventricular Failure in Cardio-Thoracic Surgery: Is One Better than the Others? (J Clin Med) (2024)

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Novel inhaled pulmonary vasodilators in adult cardiac surgery: a scoping review (Can J Anaesth) (2021)

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